The article includes materials reported on February 16, 1954 prof. A. X. Sarkisov at the plenary meeting of the Scientific and Technical Council of the USSR of the USSR.
In the light of the decisions of the January Plenum of the CPSU Central Committee on an increase in the production of livestock products, the tasks of reducing losses in animal husbandry from infectious and non-disseminated animal diseases are of particular importance to the veterinary workers.
The experience of the work of advanced farms and the best veterinary workers suggests that the incidence and case of livestock can be significantly reduced. For this, along with the creation of the necessary conditions for the content, feeding of livestock and care for it, perfect methods of combating agricultural animals are used as possible.
One of the largest achievements in the field of biology can be considered the preparation and production development of a number of antibiotics. These include Penicillin, chloromycetin and its synthesized analogs (syntomicin, levomycetin), biomycin (aureomycin), streptomycin, albomycin, gramicdine and microcond.
Mold and radiant mushrooms were produced by the most effective antibiotics.
These data, as well as materials of many scientific
employees and practical veterinary specialists show that the notice of antibiotics can significantly increase the effectiveness of therapeutic and medical and preventive measures in many diseases of young and adult animals.
According to our laboratory, out of 2992 heads of young cattle, pigs and sheep of individual collective farms and state farms of the Moscow, Zaporizhia, Tula regions and the Stavropol Territory, 2901 animals were preserved when using antibiotics. Without the use of antibiotics from the born 817 calves, only in the first month fell from various diseases 193.
We summarized by us for a number of areas of the RSFSR, the Ukrainian SSR, GSSR, AzSSR and other republics show that the use of antibiotics allows you to additionally save tens of thousands of livestock heads, significantly reduce the treatment and saving the work of veterinary specialists.
This can be judged by the materials of our laboratory and other specialists reflected in Table 1.
The results of the use of antibiotics in the treatment of various animal diseases
From these table, it can be seen that the use of antibiotics in gastrointestinal diseases of calves and piglets makes it possible to additionally save from 25 to 60% of young people, reduce the duration of treatment and significantly reduce costs.
With other diseases specified in the table, despite the minor difference in the effectiveness of antibiotics compared to other methods of therapy, the duration of the disease and treatment costs are also reduced.
Currently, the expediency of using antibiotics in veterinary medicine by practical experts is sufficiently recognized. However, the methods and forms of use of antibiotics have not yet been regulated. This led to the use of extremely diverse treatment methods with antibiotics with the same diseases that caused extra costs.
For example, when endometrites in cows, some specialists are injected with Penicillin directly into the uterus, other intramuscularly. In mastitis in cows, the solutions of penicillin are introduced into the tank of the patient of the breast, others in the passagem. And in that and in another case, treatment gives a positive result, although with the introduction of penicillin into the uterine cavity or in the udder tank, it is possible to obtain an effect from 500 thousand meters. E., And with other methods - from doses of 5-10 times more, in connection with what the cost of treatment is given rise in price.
In the face of Penicillin dose pigs on the course of treatment, as well as injection varied in large limits, penicillin was used at different intervals and in a wide variety of solvents.
In order to establish the most rational system and effective methods of using antibiotics and veterinary medicine of the USSR, October 16, 1954 approved the instruction on the use of antibiotics in veterinary medicine.
In developing the instruction, experimental materials of scientific institutions were used, as well as the best experience of practical veterinary specialists and scientists on the use of antibiotics in individual animal diseases.
The instruction on the use of antibiotics in veterinary medicine recommends the methods and forms of application for various diseases of the phenomena of Cilillin, syntomicin, leftomycentny, biomycin (aureomycin), grams of cedea C and Sanazine.
Penicillin is recommended to be used with bacillirefall pigs, soy horses, pulmonary diseases and neurobacillosis of spherical animals, hoofed sheep, sepsis, Siberian ulcers, malignant swelling, pastellosis, dogs, mastitis from cows endometritis, conjunctivitis and surgical practice.
what infection calves and piglets.
Biomycin should be applied with acute gastrointestinal and pulmonary diseases of calves, lambs and piglets, as well as with pullorosis of chickens.
Saiazin is a synthesized homolog of Pyocianin - it is used in the treatment of the European and American peg of bees.
Listed in the prevention of the disease do not exhaust all cases of efficient use of antibiotics - they can be used with therapeutic and prophylactic goal and with other diseases caused or complicated by microflora, sensitive to responding to drugs.
Due to the fact that the experience of applying streptomycin, albomycin ECMOLINA, ERITRINE, the microcide in veterinary medicine is very limited, the methods of use in the instruction are not reflected.
It is assumed that, with a broad experimental program, antibiotics will be possible to additionally recommend that veterinary practice methods for the effective treatment of animals in emphysematous carbuncule, sheep enterotoxide, infectious deorming rhythm, liquidellese, trichomonosis of large-scale cattle, dysentery of lambs and other contagious and unsuccessful diseases Levories, damage to animal husbandry. For this, further research should be conducted on clarifying the most effective methods of using antibiotics.
We will dwell only on some issues of the application of penicil Lina and Biomycin.
Currently, the following Penicillin preparations are used: sodium (amorphous) salt, sodium and potassium crystal villages, sodium and potassium technical crystalline salts, new cainy and calcium salts.
The first two - sodium and potassium crystalline and amorphous salts are used for injection and for local applications, Novocaine - only for injections, and calcium, sodium and potassium technical salts of Penicillin - only for local applications. It is known that after the introduction of sodium (potassium), Penicillin salts quickly stands out from the body with urine. This greatly complicates the treatment process. The proposed numerous methods for lengthening the actions of Penicillin have not yet been found in the veterinary medicine. By research, we found that the dynamics of the release of penicillin in different species of animals is non-etinakov. By introducing a highly concentrated solution (100 thousand ml. 1 ml) of the sodium salt of Penicillin, the time of finding the medical concentration of penicillin in the horse's body we managed to increase on the B-8 hours. However, this technique did not give results from cattle, sheep and pigs.
Unlike the sodium salt of Penicillin, the novocaine salt has a longer action. After a single injection of a novocain salt with adult horses and cattle in a dose of 4-5 thousand meters e. An animal's weight kilogram can detect the presence of penicillin in the serum of animals for 24-30 hours, the same therapeutic concentration is registered only for 15 hours at a dose of 10 thousand units per kilogram of animal weight. Thus, despite the fact that the sheep on a kilogram of the animal weight was obtained twice as compared with large animals, the duration of the antibiotic was two times less.
These studies give us reason to believe that in the treatment of novocaine salt of penicillin, a dose of 2-5 times should be increased against the fission-recommended for sodium salt, and the amount of injection is reduced to one time per day for horses and cattle, and for sheep - up to two times per day.
The novocaine salt is insoluble in water, and therefore, with intramuscularly, it is necessary to take the needles of a larger diameter and prevent falling out of precipitation in the syringe. If the precipitate appeared, then it is necessary to obtain a syringe to obtain a uniform suspension of the drug, and then produce injection.
Penicillin mainly provides the therapeutic effect only with those diseases whose detectors are predominantly gram-positive microorganisms. In contrast, other antibiotics are effective in diseases caused by both gram-positive and gram-negative microorganisms. Biomycin has such properties - one of the best antibiotics recommended in medical practice in dysentery, pneumatic pneumonia, typhoid, brucellosis and other severe diseases of people. Recently, work is underway to find methods for its use and in certain diseases of animals.
Biomycin (an analogue of aureomycin) is produced by a rainy rush Actinomyces aureofaciens. It is a crystalline powder of golden yellow color, bitter taste. Water solubility: 13 mg in 1 ml at 18 °. At room temperature, aqueous solutions can be maintained no more than a day. In solution of strong acids and alkalis, biomycin is easily destroyed.
The activity of biomycin (salty-sized) is expressed in units of action. Biomycin is available on sale with an activity of about 1000 units in 1 mg.
As a result of the integrated work of employees of our laboratory in collective farms and state farms, a high value of biomycin was revealed in some diseases of calves, piglets, lambs and chickens.
Before testing biomycin on naturally sick animals, we nose a number of laboratory studies in order to determine the optimal doses and the multiplicity of its use. Experiments were delivered on horseback, sheep, pigs and partially on a major horns
tom Skot.
Most experimental animals, the drug was used to orally but, and a cattle cattle - subcutaneously at a dose of 10, 20 and 30 mg per kilogram of the animal weight. At the same time, a number of studies were carried out to identify the duration of biomycin in the body, the dynamics of suction, distribution paths and its reservation sites in the body. For this purpose, experimental animals periodically took blood samples. In addition, it was performed by selectively slaughter animals and selected the necessary material: the contents of the gastrointestinal tract, biological fluids of the body, as well as slices of organs. Using the microbiological method for determining antibiotics, we investigated the assembled material for the content of biomicine in it.
Table 2 present the results of the blood test of horses, sheep and pigs.
Results of blood testing of experimental animals after the introduction of biomicine
From these studies, it can be seen that after one-time oral application of biomycin, its presence in the body of animals can be installed for 24-30 hours. However, the maximum accumulation of biomycin in the blood of animals was noted by 6-8 hours, after that, there was a gradual decrease in its amount in the blood. In sheep we managed to capture an antibiotic in the urine and milk for 24-48 hours from the moment the last administration of the drug.
Clinical observations noted that different types of animals reacted unequally on the maximum doses of the drug used in our experiments. The most sensitive was the horses and least sensitive pigs.
In accordance with the obtained experimental data, we developed and experienced the methods of using biomycin with gastrointestinal and pulmonary diseases of piglets, calves and lambs.
In the treatment of piglets, patients with toxic dyspepsy, biomycin was used in an aqueous solution. To this end, they took 1 g of the drug per 100 ml of boiled, chilled water. The prepared antibiotic breeding was set orally twice with an interval of 7-8 hours. In the first category of piglets, a drug was obtained at the rate of 20 mg (2 ml of solution), and in the second - 10 mg (1 ml of solution) per kilogram of the animal weight (Table 3).
Results of biomycin's use with piglets
From the given data it can be seen that the use of biomycin led to the recovery of most animals in the first day. As a rule, 7-8 hours after the first admission of the drug, the symptoms of the disease became less noticeable and the next day a clinical recovery was noted. If the patients came to treatment in a non-time, the two-time dacha of the antibiotic did not always lead to the termination of diarrhea, and the course of treatment had to be repeated the next day.
During the treatment of patients, biomycin contributed to improving the appetite and thus eliminated the possibility of losing their weight and retardation in growth.
Similar results were obtained in the treatment of toxic dyspeption of young cattle.
We applied biomicine 73 animals in farms where toxic dyspeption of newborn calves was detected. Of the 41 calf, which entered the cure, 18 were in very serious condition and were considered hopeless.
Biomycin was given according to the following scheme: the first dose - 15 mg per kilogram of the animal weight, the next three cottages - 10 mg per kilogram of the weight of the animal every 6 hours. In this case, a one-time dose was dissolved in 30-50 ml of boiled water and set the calves 30 minutes before feeding. In all cases, after 6 hours after the first giving of the drug, the animal condition improved and appetite appeared. In subsequent time, there was a further extinction of the symptoms of the disease and to the outcome of the first, less often the second, day, clinical recovery occurred.
The rest of 32 newborn calves we set biomycin with a prophylactic goal along the same scheme as in the treatment. The first dose of calves was obtained 30 minutes before the dacha of the first portion of the colostrum and further during the day with the specified intervals. No calf receiving biomycin did not get sick toxic dyspepsia. In contrast, in the control animals after 6-24 hours, a typical disease clinic was noted.
In addition to the treatment of toxic dyspepsia, we checked the effectiveness of biomycin at bronchopneumonia in 28 calves. Under the supervision there were animals in the initial stage with severe clinical signs of the disease: increased temperature (41 ° and higher), rapid pulse and difficult abdominal breathing. In these cases, the biomycin dacha scheme was similar to the toxic dyspepsia used, but the term of treatment was extended to three days with repetition of the course of treatment after 2-3 days. As a result, 26 calves recovered, 2 calves fell.
Under diploscopococcal infection, Biomycin lambs experienced in one farm, where the diagnosis was confirmed by bacteriological studies. Under the supervision was taken 40 lambs with the clinic of the disease. As a result of the experience, 37 lambs are heal.
Biomycin was asked orally three times a day every 6-8 hours at a dose of 10 mg per kilogram of the animal weight according to the scheme: three days of treatment, two days a break and then the course of treatment was repeated.
Biomycin turned out to be a very effective drug as well as Pulloroz chickens. According to the developed laboratory, the methodology, in disadvantaged farms, biomycin was applied on four birds of birds with a livestock of more than 10 thousand chickens. The departure in these farms before the use of the antibiotic reached 40-65% of chickens from all received parties. With a timely gathering of the antibiotic, the waste of chickens decreased to 2-8%. In case of late application, somewhat higher.
The daily dose of biomycin per 1000 chickens is 1 g. This dose is divided into three equal parts and dissolved at the rate of I g per 1 liter of water, added to the feed and are thoroughly mixed. Biomycin give chickens from the first day of receipt of them from incubator-poultry stations for 20-30 days.
Absolutely new is the possibility of applying antibiotics of young animals and birds in order to preserve them, accelerate growth and increase the lead.
Currently accumulated data indicate that the addition of antibiotics in minor quantities contributes to the normal growth and development of young pigs and birds. However, the essence of the stimulating effect of antibiotics on the body of young animals is completely unclealed.
In our experiments set in poultry farms (journal. "Poultry farming" No. 7, 1954), it was revealed that with the feeding of small doses of antibiotics, the waste of the chickens decreased in two or three times, and the raises rose by 10-20% rice . 12).
The method developed by us was later with the direct participation of the laboratory staff subjected to a thorough industrial inspection on the hundredsmatic poultry population in collective farms, state farms and in poultry farms of various zones of the Soviet Union.
The essence of this method is that since daily age, during the first 30 days, the chickens are obtained with feed penicillin or biomycin at the rate of 40 mg of penicilline technical salt or 20 mg of biomycin per kilogram of feed. In terms of collective farms, it is more convenient to calculate the amount of antibiotics on the bird's head (Table 4).
Daily dose calculation of antibiotics
The daily dose of one of the antibiotics given in the table is divided into two equal parts and is asked with food in the morning and in the evening.
Before adding into feed, antibiotics are dissolved in tap water at the rate of 1 g (1 million m. E.) Per 1 liter of water. Such a solution is added to food in the manufacture of feed mixtures intended for the corresponding age group of chickens.
A similar effect of antibiotics in the conditions of farms was revealed during the cultivation of piglets. The use of biomycin and technical penicillin by subference pins contributed to an increase in the skills by 20-40% and preimblocked the emergence of gastrointestinal and pulmonary diseases (Fig. 3).
The use of antibiotics to stimulate the development of piglets-sausages is most convenient to start with their milk with milk - teachments to feed. Antibiotics are asked in increasing doses of pins-sausages of 2-3 mg in the first decade, in the second decade of 4-6 mg and to the third to 8-10 mg on the head twice a day - in the morning and in the evening.
For this, penicillin or biomycin is dissolved in boiled cold water at the rate of 1 mg per 1 ml (1 g per 1 liter of water). With the help of a syringe or menzurki, the required amount of prepared solution is measured on each socket and add to the milk or, diluting in water, is thoroughly stirred with food intended for piglets.
Weak, underdeveloped piglets should be given from 1-3 days to set antibiotics to each individually in the specified dilutions and doses by dropping through the rubber tube with a syringe before teaching them to milk or other stern.
Piglets-taking twice a day, penicillin or biomycin is added to the feed at the rate of 20 mg of the antibiotic per 1 kg of feed concentrates, to which antibiotics have already been added, you cannot be deposited or any other processing.
In conclusion, it should be emphasized that the possibilities of using antibiotics in animal husbandry are far from being exhausted.
It is necessary to carry out further organizational events regarding the uninterrupted supply of veterinary institutions with the necessary antibiotics, the right use of them in the field.
An urgent task is to study therapeutic and preventive properties of developed antibiotics in cases where the effectiveness of them is not yet clarified, and the research of new antibiotics. For the performance of these tasks, our scientific and educational veterinary institutions should seriously take.
Antibiotic, low-oxidal, crystalline powder golden yellow color, odorless, taste is bitter. Weakly dissolve in water. Used in the fight against infectious diseases, as well as for healing mechanical damage to the exterior cover of fish. Apply from the calculation of 1.3-1.5 grams per 100 liters of water. The temperature in the aquarium does not increase. Filters can work. The duration of treatment from 10 days to the month. Every seven days in the aquarium add another dose of biomycin. At the end of treatment, water in the aquarium does not change.
Biomycinum - antimicrobial, anti-bacterial agent, crystalline salt-oxidized salt of chlorofacing antibiotic (hydrochloride chlorofatercycline), obtained from culture fluid Actinomyces aureofaciens fungus.
Indications for the use of biomycin. Biomycin is used for the treatment of pyodermias, oxidic skin diseases (folliculitis, furuncoolosis, etc.).
Terms of application. Inside, biomycin is prescribed 100,000-500,000 units on the reception 4-6 times a day, the daily dose of the drug is 2,000,000 units (2 g).
Biomycin children are prescribed from the calculation of 25,000 units (0.025 g of the drug) per 1 kg of body weight of the child's body per day.
Examples are externally used (immediately before use) aqueous biomycin solutions at a concentration of 4000-5000 units of an antibiotic per 1 ml solution.
Shelf life and storage conditions. Store in a dry, cool, light-protected place.
Synonyms: Aureomicoin. Aureomycin. Chlortotracycline hydrochloride.
More antibiotic - white streptocid.
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The site provides reference information solely to familiarize yourself. Diagnosis and treatment of diseases must be under the supervision of a specialist. All drugs have contraindications. Consultation of a specialist is obligatory!
Drug Treatment Banocin represents antibioticwhich is used exceptionally externally. Baneocin is successfully used to treat dermatological diseases, in gynecology, in the practice of doctors - otolaryngologists, as well as pediatricians. Efficiency and high security make it possible to apply it for the treatment of children, including newborns.
Antibiotics neomycin and Bacitatzin as active actants of the drug Baneocin give and ointment, and a bactericidal powder. Both antibiotics enhance each other's action. This means that Baneocin is able to effectively kill microorganisms existing on the skin or in wound surfaces. Thus, the main therapeutic effect of the drug is the curable of infectious-inflammatory lesions of the skin, which are caused by microorganisms sensitive to components of ointments and powder. Baneocin ointment or powder is successfully used to treat various infectious inflammatory diseases, which are caused by microorganisms sensitive to the active components of the drug. Basically, Baneocin ointment is effective in treating:
Baneocin powder is also effective for the treatment of infections localized on the surface of the skin. The drug is successfully used in windmill, herpetic rashes, ulcers and eczema, as well as for processing navels in newborns, postoperative seams, including postpartum injuries (crust and other). Banocin powder also has a powerful antibacterial property, which allows you to destroy the causative agent of infection, accelerate the healing of wounds and traumatic skin damage, as well as reduce the severity of inflammatory processes.
Indications for the use of Baneocin powder in various fields of medicine are reflected in the table:
| Sphere of medicine | Powder - Indications for use | Ointment - Indications for use |
| Dermatology | Treatment and prevention of guns, pimples | No severe infections of skin and mucous membranes - Contantagious impetigo, boils and carbuncules |
| Treatment and prevention of infection of small wound surfaces | Folliculitis and deep folliculitis on the scalp | |
| Processing of the wound and small surgical cuts and punctures (ear dump, navel, excision of scars, cavity, skin transplant, cracks, wound wounds, etc.) | Purulent hydragenite (inflammation of lymph node) | |
| Treatment of burns | Sweat gland abscesses (pseudofurunculosis) | |
| Treatment of infections of traumatic wounds (scratches, cuts, etc.) | Abscesses on the skin | |
| Treatment of bubbles on the skin with windmill or herpetic infection | Paronichia | |
| Infected trophic ulcers in varicose | EXIMA | |
| Eczema | PODERMIA (multiple mouth lesions) | |
| Infection of dermatosis (ulcers with eczema, etc.) | ||
| Treatment of infection and its prevention at traumatic, surgical or cosmetic damage to the skin (burn, skin transplant, puncture ear, cuts as a result of edged manicure, etc.) | ||
| Infected trophic ulcers in varicose | ||
| Gynecology | Treatment of crotch or cuts (episiotomy) | Treatment of crotch breaks |
| Treatment of mastitis with drainage | Application at laparotomy (operation with an opening of the abdominal cavity) | |
| Prevention of mastitis | Crotch cuts treatment (episotomy) | |
| Treatment of mastitis with drainage | ||
| Prevention of mastitis | ||
| Otolaryngology | Treatment of secondary infections in acute and chronic cold | |
| Treatment of outdoor otita | ||
| Prevention of infection after surgery on the sinuses of the nose and forehead or on a predominant process | ||
| Pediatrics | Treatment of umbilical wounds for infection prevention | |
| Treatment of diaper dermatitis |
Children and adults should apply ointment or powder locally, strictly on an infected area. You can simply apply the ointment on the affected place or spray it with a powder of Baneocin, and you can cover the processed bandage from above. The processing of the affected sections of the ointment Baneocin is carried out two or three times a day, and the powder is sprinkled 2-4 times a day. If burns are tested, which capture more than 20% of the body surface, then the processing of the Baneocin powder is carried out once a day. Such a restriction is associated with the possibility of suction of the drug in the bloodstream. However, during the use of the drug, no overdose case was recorded.
In the treatment of Baneocin, there is a maximum allowable dose, which is 1 g of the active substance per day, which corresponds to 200 grams of powder or ointment. With such dosages of the Banocin, the course of treatment is 1 day. If, after using ointments or powder in maximum doses, a second course of treatment with Banocin is needed, then permissible dosages are reduced by two times. Treatment with exceeding the specified maximum dosages can lead to the suction of a large amount of Baneocin in the blood, which is fraught with a high risk of toxic damage to the kidneys and ear. Therefore, therapy with large doses of ointments or powder should be carried out under observation, with careful control of the presence of symptoms of kidney damage or ear.
Banocin powder with windmill will excellently replace the traditional greencraft, the efficiency of which is lower, and cosmetic properties are not too good. Powder removes itching at the site of the bubble, which prevents combing sacing by children. Banocin for sprinkling bubbles with windmill can be used both children and adults.
With burns, every person at least once came across a life, especially in childhood, when a child sheds hot water, accidentally concerns a hot plate or fluff, etc. The burn surface is a gate for infection that joins very often. Therefore, the healing of burns can be long. Infection of the burn wound leads to a deterioration in the state of the person, regardless of the area of \u200b\u200bthe affected skin. Infection can deepen the burn and prevent independent healing of the wound surface. An excellent means for the treatment of burns of the 1st, 2nd and 3rd degrees with different areas of the lesion is Baneocin. The burns of the 1st and 2nd degree are quite common in children. Their distinctive feature is wearing leather, bubbles or just red. Such burns can be treated at home. Baneocin is also suitable for emergency processing of the burn wound immediately after the incident occurred.
The processing of the burn wound by Baneocin is painless, is very well tolerated and not accompanied by unpleasant sensations. Therefore, Banocin powder is a great preparation for the treatment of burn at home. The processing of the wound surface should be done twice a day, until complete epithelization, which usually occurs after 7 - 10 days. Sometimes burn treatment with the drug can provoke allergies, redness, itching and dry skin.
The use of banocin for the treatment of burns of a 2nd degree significantly reduces the deepening of the lesion, speeds up the process of healing and restoring normal skin. The effectiveness of the drug is due to a significant decrease in the risk of infection of the wound and the creation of favorable conditions for healing and restoring the skin.
Since Baneocin is an antibacterial drug, it can be used to treat acne, acne rashes and inflammatory races on the face, especially purulent. Dermatologists recommend to apply Baneocin ointment once a day, before bedtime, point to acne and rashes, if there are few of them. If the acne and acne on the skin are much, then the ointment is applied to the entire affected area completely. Ointment should be applied with a thin layer in the evening, and leave for the night. In the morning you need to wash your face and refresh it to Tonic. Daily ointment Baneocin to treat acne can be applied from one week to two, after which it is necessary to take a break. Then, if necessary, the course of treatment can be repeated. However, in most cases, 2 - 3 treatments are quite enough to eliminate acne and acne. Even strongly inflamed acne is significantly reduced in size under the action of Banocin, after which they heal. You can use ointment and for the prevention of the formation of guns in the place of extruded pimples. For this evening, extrude all the pimples, comedones and acne, put the ointment of Baneocin on these places and go to bed without flushing the drug. In the morning, the skin is usually clean and smooth, there are no traces from extruded pimples, no red spots or gunnings. In the morning you need to wash your face with warm water and rub the tonic.
In addition, the side effects of Baneocin include allergic reactions at the place of application of the drug - it is redness, leather drying, rash and itching. In rare cases, the development of allergies in the form of contact eczema is possible. Such a type of allergic reaction in half cases is associated with cross-allergies with other antibiotics - aminoglycosides (for example, Kanamycin, Tobramycin, amikacin, gentamicin, etc.). Therapy of chronic medium otitis or dermatosis can lead to a decrease in sensitivity to other drugs, causing the small effectiveness of the treatment.
Both ointments contain antibiotics as active ingredients. However, Levomecol contains only Levomycetin antibiotic, and Baneocin is neomycin and Bacitracine. Therefore, Baneocin is more effective in relation to infection than Levomecol. Levomecol has an additional property - contribute to scarring and rapid healing, but the ointment has a rather strong irritant effect. Both drugs are tested by time, and have excellent efficiency. Levomecole is produced only in the form of ointments, and Baneocin is also a powder. Therefore, for sprinkling the wound, scratches, bites and other damage to the skin in children - is undoubtedly more convenient and practical Banocin. But adults can use Levomecole. Nevertheless, experts consider the antibacterial effect of Baneocin as the best, compared with the levomecommium. Therefore, it makes sense to make a choice in favor of Baneocin. If financial capabilities do not allow, it is better to acquire levomecol - its cost is less.
One of the best antibiotics, overwhelming and causing the death of microorganisms in dysentery, abscessive pneumonia, diseases of the brushing, abdominal typhoids and other severe diseases of people is Biomycin. Instructions for use describes it as a drug that can simultaneously influence various microbes and is often used in therapeutic and preventive purposes. In addition, Biomycin is used to stimulate young growth as
Biomycin is an antibiotic that is produced by Actinomyces aureofaciens microorganism. A drug is produced in the form of a yellow crystalline powder, a bitter taste, but not smell. Poorly dissolved in water (at a temperature of +18 only 1.3%), the solutions of yellow color; ranges from 2.7 to 2.9.
The drug is resistant in a weakness medium and in air, but it is easily destroyed in alkali solutions and strong acids. The chemical structure allows "Biomycin" to the group of tetracyclines, which also includes Terramitsin, Tetracycline and Oxytetracycline.
The activity of the drug is determined by the results of biological standardization and is expressed in units of action (units) or in weight relations. One unit is equal to 1 μg of chemically pure chlorohydrate chlorofitracycline.
Ointment "Biomycin" Instructions for use describes as suspension of solid particles in the aqueous phase of the emulsion. Conducted by insignificant solubility in water.
Biomycin, possessing a wide antibacterial spectrum, is effective in relation to both gram-positive and gram-negative bacteria, as well as rickettsis and certain types of viruses.
Biomycin in the form of a solution, ointment or powder can be appointed for intramuscular administration, as well as outdoor and internal use. With this antibiotic, many infectious diseases are treated (malignant carbuncoon, necrobacteriosis, Balkan influenza, dysentery, chicapatifoic infections). At the same time, semi-finished products of the drug, which are added to the feed, accelerate the growth of young people. Biomycin Instructions for animal use recommends using a gastrointestinal tract and pulmonary diseases of the grooves, calves and piglets, as well as with pullorosis of chicken chicken.
This broad-spectrum antibiotic is permissible to use and for healing mechanical damage to the covers of aquarium fish.
As for the contraindications, the use of "biomycin" is unacceptable with increased sensitivity to components included in its composition.
Biomycin (Powder) Instructions for use recommends using for the preparation of solutions for intramuscular administration. Despite the fact that the drug itself has excellent therapeutic effects, the best effect is achieved with simultaneous reception with sulfanimide means (with a calculation of 0.1-0.2 g per rabbit).
In the treatment of hemorrhagic septicemia, the recommended dose of the antibiotic is determined taking into account the weight of the animal (per 1 kg, it is necessary from 20 to 25 thousand biomycin units). The duration of Pastellosis therapy is 3-4 days, provided that the drug will be introduced into the body of patients of rabbits twice a day.
In the chronic form of hemorrhagic septicemia, treatment is carried out otherwise: the first 3 days the animal gives preparations with a wide range of bacteriostatic action, which are included in the group of derivatives of sulfanyl acid derivatives, then the same days - Biomycin, and at the end, sulfonamide products.
When taking antibiotics, it is necessary to refrain from feeding with a silo with a silos, which can provoke the appearance of diarrhea.
The "biomycin" solution is introduced by animals in the latent period, for some time before vaccination. The interval between the first and second injection must be at least 8 hours. Thanks to the use of Biomycin, the animal is saved from possible death.
Inside the antibiotic is prescribed rabbits in diseases of the gastrointestinal tract, less often - with colds. Recommended dosage in these cases - 0.1 -0.15 g twice a day with the duration of treatment from 3 to 5 days. In order to prevent the occurrence of coccidiosis "Biomycin", the application instruction allows for hazing in a mixture with food at the rate of 0.01 g per animal. Prevention is recommended to continue for 5 days.
Within 1.5-2 months to accelerate the growth and development of young, since the 20-day age, it is possible to give 0.005-0.1 g of the preparation "Biomycin". Instructions for use in veterinary medicine indicates that when non-compliance with the recommended dosages and the timing of the use of the antibiotic rabbits may die. This is due to the poor tolerability of the drug.
Exceeding recommended doses of Biomycin may cause poisoning. In the case of using the drug longer than the appointed period, the appearance of stomatitis, vomiting, diarrhea and edema is possible. If such side effects appear, it is necessary to reduce the dose of the drug or to abandon use. Decide will help the veterinarian after the degree of intolerance to the drug will be established.
According to the laboratory data obtained in the Belarusian Research Institute of Livestock, with the use of feed "Biomycin" for two months, the growth of chickens accelerated by 25.5%, with the use of a pure drug - by 21%. When feeding the birds with a feed and feed vitaminized means, their weight increased by 27-29%.
The mass of broilers, which were fed by "biomicine" to two months of age, ranges from 1.5 to 1.7 kg. This is quite logical, because under the action of antibiotics, the growth and development of chickens is accelerated. This drug is in great demand among people engaged in the cultivation of birds for sale, because when taking Biomycin, the growing time is reduced from 91 days to 70.
Approximately the same reaction to the antibiotic in the turkey, ducklings and geussing. Biomycin is recommended not to be given in pure form, but with feed.
Biomycin (instructions for use indicates this) It is necessary to keep in a dark and dry place, where the temperature does not rise above 20 degrees. The shelf life of the drug is no more than six months.
Despite the fact that the reviews of this antibiotic are predominantly positive, some people involved in breeding farm animals are forced to abandon the use of Biomycin due to the difficulties that arise with its acquisition in Russia. In veterinary pharmacies, mainly foreign analogues of the drug are offered.
Bacterial and viral diseases are a serious enemy of farms. In most cases, it is necessary to connect "heavy artillery" in the form of antimicrobial antibiotics. Biomycin - a wide action medicine, effectively with many illnesses. This instruction will help to figure out, in what cases and how to use the tool.
Biomycin is an antibiotic that is produced by Actinomyces aureofaciens microorganism. The tool suppresses the work of a large number of pathogens and bacteria. Effective with respect to GR + and grothed microbes.
It is used in the treatment of the following diseases in animals:
Attention! According to the instructions for use, biomycin is used to treat covers even among aquarium fish.
The agent is made in the form of powder crystals, odorless, pale yellow. Resistant to air and solubility in water is rapidly destroyed when acid and alkaline solutions are exposed. Available in the form of a finished solution, powder or ointment. As a rule, the glass containers are glass. Based on the powder mixture, medicine is divorced for injection. Ointment - for outdoor application.
Instructions for use gives a detailed composition of biomycin. It is related to a number of "tetracycline" due to its main actant. Biomycin does not have a "accumulative" effect, quickly affecting pathogenic bacteria, is excreted through the kidneys.
Biomycin is successfully used to combat launched disease forms. Thanks to its gentle influence on the gastrointestinal tract, the medicine is used in the treatment of intestinal viral infections. Each type of animal perceives biomycin in different ways (like other drugs). The treatment and accurate dosage can be assigned only veterinarian. It will decide on the weight, condition, age and mass of the animal. Particularly careful biomycin should be used in the treatment of rabbits. With the slightest overdose, the medicine may be toxic. In the application instructions, the optimal dose is indicated - 0.1-0.2 g per animal.
Attention! In birds, the chicken detachment, biomycin is used as a stern additive. Purpose - accelerated bird growth. The term of cultivation decreases for 20 days.
Special sensitivity to biomycin manifests young. Exception, piglets having good tolerability of the drug. They use a drug in the form of a solution for oral administration. The effect of treatment of piglets is observed almost immediately after the start of treatment. For the prevention and active growth of animals, young people give biomycin in a solution with milk, immediately after appearing on the light and 3 days after. Use in the treatment of cattle:
In general, the drug has proven itself, both as part of complex therapy and being the only treatment in the treatment scheme. Specifies quickly, symptoms of the disease (dysentery, type, staphylococcus) disappears from several hours after use until 2-3 days. As a vitamin additive causes a rapid growth of young, increasing productivity. As an outdoor tool in the form of ointments, helps to get rid of skin ulcers and dermatitis. The main contraindications for the use of drug are individual intolerance and overdose. In the first case, the drug is canceled if the dose is exceeded by the symptoms of the consequences, reduce the dosage or change the medicine to another. In any embodiment, the decision is taken after an inspection of the animal veterinarian.
Biomycin manufacturer (as stated in the instructions for use) regulates a dry and dark place to store the drug. At a temperature of not more than 20 degrees. The total shelf life is 6 months. When buying a tool, it is important to be confident in the reliability of the network for biomycin. The use of fakes is fraught with animal death! After consulting a veterinarian, it is possible to use other drugs of the same series, for example, oxytetracycline, terrarsicin.
Biomycin is a multifunctional antibacterial agent, widely known in the circles of animals. By deciding to use the drug for treatment and prevention, it is important to discuss it with a veterinarian. Incorrect or excessive use of the drug may damage instead of the expected positive effect!
