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Furazolidone. What parents need to know

The children's body is very often exposed to infections, including intestinal ones. Due to their age, a small person is not able to control personal hygiene or the freshness of the products used. Therefore, pathogenic bacteria sometimes settle in the child's body, causing gastrointestinal disorders. Often it is not possible to establish the causative agent of the disease even in laboratory conditions. In this case, doctors prescribe broad-spectrum antibacterial agents. Before giving your baby one of these drugs, such as Furazolidone, read the instructions for use for children.

Furazolidone is an antimicrobial agent. Belongs to the group of nitrofuran derivatives. This is a synthetic drug with the active substance furazolidone and auxiliary components - silicon dioxide, calcium stearate, glucose monohydrate and potato starch.

In children, as in adults, Furazolidone is easily absorbed through the gastrointestinal tract and is rapidly distributed throughout the tissues of the body. It is inhibited in the liver into an amino derivative and is excreted mainly in the urine (up to 65%), coloring it in a characteristic yellowish tint, and partly in the feces.

Available in 2 forms:

  • Tablets containing furazolidone 50 mg.
  • Granules for the preparation of a suspension of 50 or 100 g in a 150 ml vial.

It is believed that in the treatment of intestinal and some other infections, it is preferable to use Furazolidone for children over antibiotics. It does not suppress the immune system and acts much softer. In addition, pathogenic bacteria develop resistance to it more slowly.

Indications and methods of administration for children

Before giving Furazolidone at the first sign of malaise, it is necessary to conduct an examination and consult with a pediatrician. A child's complaints of abdominal pain do not always mean an acute intestinal infection and require immediate medical treatment. The drug is prescribed only if the doctor confirms the infectious nature of the disorder.

The most common ones may be:

  • Various forms of dysentery (infection with shigella).
  • Paratyphoid (spreads salmonella).
  • Food poisoning.
  • Giardiasis.
  • Rod or coccal infections.

During an acute GI disorder, the child may develop fluid or electrolyte imbalances due to frequent vomiting and diarrhea. In addition to antibacterial treatment, it is necessary to rehydrate (replenish the volume of fluid) and restore the intestinal microflora. There are special medicines for this.

The use of nitrofurans for the treatment of bactericidal invasion of a child is possible only from the age of twelve months. It is strictly forbidden to prescribe them to children under one year old in any of the manufactured forms.

Until the child is 5 years old, the only possible way to treat with Furazolidone is to use a suspension. It is obtained from a granular powder, diluted with warm boiled water to the desired volume. For children older than five years (with rare exceptions, treatment at 3 years is allowed), the drug can be given in tablets.

Dosing features

The daily dose is determined by the weight of the child. The calculation should be 10 mg per 1 kg of body weight. The resulting figure must be divided into three or four doses. The medicine is given strictly after meals at regular intervals. If these are tablets, then they are washed down with plenty of water. The duration of treatment can be from 3 to 5 days. The maximum course of therapy is limited to ten days.

Illustrative examples of how to give Furazolidone to children:

  • The sick baby is 2-3 years old and weighs almost 12 kilograms. Use only suspension. The volume of the daily dose of the drug will be - 10 ml * 12 kg = 120 ml. Divide into 3-4 equal parts and calculate a single reception. It turns out that the baby should be given 30 or 40 ml of Furazolidone once a day, respectively.
  • It is supposed to treat a child older than six years, whose weight is 20 kg. Apply tablets. Calculate the daily volume of the drug according to the scheme - 10 mg * 20 kg = 200 mg. Similarly, divide into an equal number of doses and get 50 mg, which is equal to 1 tablet.

The duration of therapy depends on the diagnosis and severity of the disease.

Contraindications and side effects

For children, the restriction on the use of Furazolidone can be divided into 2 categories - a complete ban or careful use.

  • The child is less than 1 year old.
  • There is a history of severe renal pathology.
  • There is a high sensitivity to the components of the drug.

A number of other cases have relative contraindications, in which the appointment of Furazolidone is permissible, but this should be done with extreme caution:

  • Poor lactose tolerance.
  • Renal failure.
  • Hepatic pathologies.
  • Diseases of the central nervous system.

Side effects in the treatment of Furazolidone are rare. Sometimes these are disorders of the digestive tract and allergic reactions, less often - disruption of the nervous or excretory systems (occur in overdose):

  • Nausea, vomiting, diarrhea.
  • Abdominal pain.
  • Loss of appetite, up to the complete refusal of food.
  • Redness of the skin, rashes and itching.
  • Quincke's edema (angioneurotic).
  • Neuro or hematotoxicity.
  • Toxic hepatitis.
  • Violation of hematopoiesis.

A loading dose of Furazolidone can not always rid a weakened body of an illness without consequences.

In children, more severe consequences may occur both with errors in the calculation of the dosage of the drug, and with severe invasion, which requires prolonged treatment and large volumes of the drug.

special instructions

Can side effects be avoided? Yes, if, with poor tolerance of the drug in a child, the daily dosage is divided into five to six parts. To exclude intoxication of the body, the intake of Furazolidone must be supplemented with activated charcoal or Smecta (by age). An allergic reaction will be prevented by antihistamines.

To prevent neuritis, it is better to combine long-term treatment with a vitamin B complex. Only the simultaneous intake of all 9 micronutrients (which are considered the most important from group B) enhance their action and trigger the natural restoration of various nervous functions. In addition, their analgesic properties have been proven. The norm of these drugs is determined by the pediatrician.

If treatment with Furazolidone lasted a week, and there was no improvement, it is necessary to stop taking the drug and reconsider the method of therapy and the type of drug. The same applies to the well-being of the child. Frequent complaints of malaise or an increase in unpleasant symptoms indicate that the drug is not suitable for the little man and causes complications.

Analogues that are suitable for children

An analysis of the pharmacological market shows that other drugs with the active ingredient furazolidone are not produced. But in pharmacy chains you can find similar analogues, including those available for the treatment of children. They differ in active substance, but are very similar in effect.

Many of these drugs are available in the form of tablets, others in the form of a suspension, which is also convenient for the treatment of a small child. Furazolidone analogues can be considered:

  • Enterofuril. Available in the form of a suspension or capsules. Its active component is niforoxazide. This is one of the most expensive substitutes for Furozalidon. Its price is justified by the quality. The chemical composition of the drug has a higher purification, and, according to manufacturers, has less negative impact on the body.
  • Nifuroxazide. Tablets and suspension for children. The drug is also a derivative of nitrofuran with the active ingredient - nifuroxazide. Suppresses the vital activity of bacteria that cause intestinal and other infections.
  • Ftalazol. Release form - tablets. The active substance is phthalylsulfathiazole. Inexpensive and effective drug against many anaerobic bacteria.
  • Stopdiar. Coated tablets are available for adults, suspension for children. The active ingredient is nifuroxazide. Kills various strains of bacteria and viruses.

There are many other substitutes for Furazolidone. Each atypical situation in the treatment of infectious invasions requires an individual approach. Most of all, this is typical for pediatric therapy. Only a complete examination of the condition of a sick child and its features allows the doctor to make the right choice of the drug. Self-medication is always dangerous, both for an adult and for an infant.

Among the parents who treated their children with Furazolidone, there are many good reviews, but there are also ambiguous ones. As a plus, the affordable price of the drug is often noted. For people who are not the first time resorting to the help of Furazolidone, it is considered an indispensable medicine for a home first aid kit. This category of patients states rare and minor side effects with a quick recovery of the child. There are also rather suspicious mothers and fathers, who are forced to refuse treatment with this drug by an impressive list of contraindications and negative consequences.

The drug Furazolidone for children from 3 years old is prescribed by the attending physician. As you know, the body of a baby at the age of 3-5 years is very sensitive to most infections and diseases. Intestinal infections are no exception. A young developing organism is not yet able to withstand harmful microbes. And they, as a rule, affect the child's body, including the digestive system. This creates a threat of the spread of the pathological process to other organs. But do not despair, because Furazolidone can come to the rescue, the reception of which will help protect the child.

It should be noted that the effectiveness of Furazolidone is much higher than that of such agents as Furacilin, Furagin. As for toxicity, Furazolidone in 50 mg tablets is approximately 4-5 times lower than other similar drugs. And since, with the activity of Furazolidone in tablets, bacteria release much less toxins, the child's recovery, as a rule, occurs very early, even before the pathogenic microflora is completely suppressed. One of the possibilities of the remedy is to stimulate the protective function of the body and the ability of leukocytes to destroy harmful microorganisms.

When Furazolidone tablets are prescribed: instructions for use will tell you. Children's Furazolidone or Enterofuril in tablets of 50 mg is used for infections of the gastrointestinal tract, such as:

  • infectious food poisoning of the body;
  • salmonellosis and giardiasis;
  • cholera;
  • diarrhea and vomiting.

Diarrhea, like vomiting, is not a disease in itself, but they are considered symptoms of intestinal disorders. The occurrence of these problems is a sign of the alleged disease of the body. It is especially worth paying attention to diarrhea, since it is she who is the precursor of other intestinal infections in the baby's body.

Parents need to know that although diarrhea is only a symptom, it is one of the leading causes of death in children aged 3-4 years. After all, even the most common diarrhea can lead to exhaustion and dehydration of the child's body. And also diarrhea can remove almost all the useful substances necessary for life support. However, not only diarrhea, but also vomiting is a very dangerous phenomenon at this age.

Furazolidone for children is exactly the medicine that is used to prevent the manifestation of the above symptoms, regardless of what disease caused them.

How to take Furazolidone

Furazolidone for children in 50 mg tablets, like other drugs, has its own instructions for use, which must be studied before treatment.
The basic rule of thumb is:

The drug is given to the child after a meal, so that it is well absorbed by the body.

In order to avoid any side effects, children are given a pill to drink with plenty of liquid.
Before using the remedy, you need to consult a doctor who can additionally select drugs that can help get a good result much faster.

As a rule, for children from 3 years old, this remedy is prescribed in the form of a suspension, which is made from granules. Yellow and green granules are used in pharmacology to make a suspension. The drug is used as follows: hot water is poured into a bottle with granules, then everything is mixed and shaken. You should get a suspension. Shake the drug before each use. The dosage should not be selected independently. It is better to trust an experienced doctor who, based on weight, height and age, is already prescribed the appropriate dosage. The course of treatment with the drug lasts about a week, but if the condition is severe, it can stretch up to 2 weeks.

Before giving a child this or that drug, parents are interested in the safety of the drug for the baby. This remedy has no contraindications. But still, there are some side effects, namely allergic skin rashes on the child's body (like urticaria), nausea, vomiting, loss of appetite, and so on. But such side effects are very rare.

The use of Furazolidone should be abandoned in cases where the child has a particular sensitivity to the components of the drug, acute chronic renal failure, liver disease and neurological disorders. If at least one of these symptoms is found in a baby, then it is better to forget about this drug so as not to worsen the situation.

If a child has contraindications to Furazolidone, then you should consult a doctor who can choose the appropriate analogue for this medicine.

Worms can live asymptomatically in your body for years and their waste products will interfere with your body and cause other diseases, the course of which often becomes chronic.

You are familiar with the following symptoms firsthand:

  • nausea;
  • gas and bloating;
  • frequent colds;
  • bad sleep;
  • weight problems;
  • excessive nervousness;
  • fatigue;
  • skin problems?

Advantages and disadvantages - acts on strains that are resistant to some antibiotics. Does not affect anaerobes and Pseudomonas aeruginosa. Microbial resistance to the drug is rare.

It is important to observe the dosage indicated in the instructions for use of Furazolidone, since the therapeutic effect of the active substance depends on the dosage - large doses achieve a bactericidal effect, and small doses achieve a bacteriostatic effect.

Can furazolidone be given to children? It is possible, for children, the drug is available in the form of granules, which are diluted in water before use. Details of the use and dosage for children are described below, and depend on the age and weight of the baby.

What helps Furazolidone?

Furazolidone is prescribed for the treatment of infectious diseases of the genitourinary system, gastrointestinal tract or skin. The main use of the drug is in the treatment of diseases such as:

  1. amoebiasis and amoebic dysentery;
  2. diarrhea of ​​infectious etiology;
  3. bacillary dysentery;
  4. giardiasis;
  5. trichomoniasis;
  6. bacterial colitis accompanied by loose stools;
  7. typhus.

You can also take "Furazolidone" for food poisoning, vaginitis, urethritis, pyelitis and cystitis. Used to treat infected burns and wounds.

Furazolidone - instructions for children

The dosage of furazolidone for children depends on the type and degree of the disease and should be prescribed by a qualified doctor. According to the instructions for use, for dysentery, paratyphoid fever, food poisoning, giardiasis, the dosage is:

Children from 5 to 14 years old - 0.03–0.05 g (for giardiasis, it is recommended to proceed from the calculation of 10 mg of furazolidone per kg of body weight per day in 3-4 doses).

For reference - 0.05 g is one tablet of furazolidone 50.

For children under 5 years of age, Furazolidone is available in the form of granules that require dilution. Boiled water is poured into a bottle with granules up to the mark on the container (100 ml of suspension is obtained) and shaken to dissolve the contents and obtain a suspension. The dosage is prescribed only by a doctor based on the indicators of the child and the weight of the baby (for 1 kg of the child - 0.01 g of medication).

You should not independently select the dosage of furazolidone for children of the year - this should be done by a doctor. Since not only weight is important here, but also the degree of full-term and other data of the baby.

The duration of treatment depends on the degree of the disease, usually up to 7 days, with severe infections up to 12-14 days.

Undesirable reactions in childhood to Furazolidone are mainly manifested at increased dosages without consulting a pediatrician during the treatment of a child at home.

The most common manifestations are a skin rash like urticaria, swelling and itching. Vomiting or nausea is possible. Symptomatic treatment is carried out as needed. It is possible to take the drug simultaneously with antihistamines to avoid allergies.

The drug is taken after meals. During the use of medicine for a child, it is necessary to carefully monitor his condition.

Furazolidone - instructions for use for adults

According to the instructions for use, for dysentery, paratyphoid fever, food poisoning, giardiasis after meals 4 times a day for 5-10 days.

Take no more than 0.8 g of furazolidone per day. More than 10 days to take Furazolidone is not recommended.

Instructions for use furazolidone 50 (tablets), single and daily doses:

With trichomonas colpitis - 0.1 g 3-4 times a day for 3 days, and at the same time local treatment is required - rectal suppositories with Furazolidone in the rectum.

With various food intoxications and dysentery, 100-150 mg is used. The course of treatment is 7-10 days.

For diarrhea in adults, furazolidone is used 2-3 tablets of 50 mg up to 4 times a day. The maximum period of use is 1 week or until diarrhea stops for a period of at least 12 hours.

For cystitis, 2 tablets (100 mg in total) are used four times a day for 4-5 days.

With trichomonas urethritis, 100 mg 4 times a day for 3 days.

According to reviews, Furazolidone is effective in the treatment of giardiasis. Adults are prescribed 4 times a day, 100 mg for 5 days.

The maximum dosage for adults is 4 tablets (0.2 g) - a single dose and 16 tablets (0.8 g) - daily.

Important. To maintain a uniform concentration of the active substance in the blood, observe equal intervals between taking Furazolidone tablets. Compliance with the instructions for use will reduce the likelihood of side effects and is the key to effective treatment.

Overdose and side effects Furazolidone

With the introduction of high doses, neurotoxic reactions, polyneuritis, acute toxic hepatitis, disorders of the hematopoietic system may occur.

To reduce the side effects of Furazolidone, it is recommended to drink plenty of fluids.

With prolonged use of Furazolidone, especially in infants, methemoglobinemia and hemolytic anemia, hyperthermia, cough, shortness of breath and neurotoxic reaction may develop.

The drug should be administered with great caution to persons suffering from diseases of the nervous system and liver.

If necessary, the use of the drug during lactation should decide on the possible interruption of breastfeeding.

Interaction with alcohol

Furazolidone in combination with ethanol can lead to the development of disulfiram-like reactions.

Composition and form of release
1 tablet Furazolidone 50 contains the active substance 0.05 g, 10 pcs in a package.

Best before date
3 years

Storage conditions
In a dry place protected from light. Keep out of reach of children.

Before using the drug Furazolidone, consult your doctor!

Furazolidone is a broad-spectrum antimicrobial agent. It is widely used for the treatment of food poisoning, inflammatory diseases of the genitourinary system, skin diseases. Can this remedy be given to children? From what age is the medication allowed? What are the reviews for this tool? Let's get acquainted with the instructions for using this drug.

Pharmacological properties

Furazolidone belongs to the group of nitrofurans. Active against gram-negative pathogens. Gram-positive bacteria, protozoa, are somewhat more resistant to it.

One of the properties of Furazolidone is the effective activation of the immune system.

The mechanism of action of the drug depends on the dosage. In low doses, it exhibits a bacteriostatic effect, that is, it prevents the growth of bacteria. With an increase in the dose, furazolidone kills microbes, providing a bactericidal effect. The drug blocks the respiratory processes in the cell, destroys its membrane.

The growth and reproduction of microorganisms are stopped due to a violation of the production of a number of proteins. Also, the drug inhibits the synthesis of toxins by pathogenic microbes, which is manifested by the rapid disappearance of clinical symptoms and improvement in the patient's condition. This is confirmed by positive feedback from patients and doctors.

In addition, furazolidone has an immunomodulatory effect. By increasing the activity of leukocytes, it enhances phagocytic processes.

Pharmacodynamics and pharmacokinetics

Furazolidone is very rapidly absorbed after oral administration. Therapeutic concentrations are reached within 4 hours after taking the medicine. Metabolism of the drug occurs in the liver, resulting in the formation of a pharmacologically inactive product. Due to the rapid neutralization, furazolidone is not able to accumulate in tissues and organs. Unchanged and modified forms of the drug are excreted by the kidneys. In patients suffering from chronic renal failure, the rate of excretion of furazolidone decreases.

Indications for use

Indications for the use of furazolidone are explained by its pharmacodynamic properties - the ability to create therapeutic concentrations in the lumen of the digestive tract and excreted by the kidneys. According to the instructions for use, the main indications for prescribing the drug include:

  • dysentery;
  • paratyphoid;
  • enterocolitis of infectious etiology;
  • giardiasis;
  • trichomonas infection - colpitis, vaginitis, cystitis, pyelitis, urethritis.

Enterocolitis of infectious etiology is the most common indication for prescribing furazolidone to children.

Furazolidone is taken orally

The main manifestation of the disease is diarrhea. But it is categorically not recommended to use the medicine on your own - diarrhea can be a symptom of another, more serious pathology.

Mode of application

Furazolidone is available in the form of tablets and granules. Therefore, it is applied orally, that is, through the mouth. For children, no matter how old they are, it is preferable to give the remedy in granules. This is due to several points. Firstly, the tablet contains a fixed amount of the active substance, so it is sometimes impossible to select the required therapeutic dose. Granules allow you to dose the drug more accurately. Secondly, it is difficult for children under the age of six or seven to swallow a pill without chewing. In addition, it must be washed down with plenty of water, which is not always possible for a child at the age of two or three years.

To prepare a suspension, boiled water is added to a vial with furazolidone granules up to the appropriate mark. The container is then vigorously shaken. After 15 minutes, the medicine is ready for use. Since solid particles settle, the contents of the vial must be shaken before each dose.

In the treatment of giardiasis, the daily dose for children is 10 mg of the active substance per 1 kg of body weight. The interval between taking the medicine is 6 hours. Therefore, the daily dose must be divided into four doses and taken at regular intervals.

In other cases, the dosage may vary depending on how old the child is.

Children under one year of age are not recommended. From one to two years, according to the instructions for use, the daily dose is 20 ml, a single 5 ml - one teaspoon. Children from three to four years old should be given 28 ml of suspension per day. Therefore, a single dose for them is 7 ml. A five-year-old child should take 34 ml of medication per day, or 8.5 ml four times a day. For the treatment of children from six to 14 years of age, the maximum single dose is one tablet, daily - three tablets. The younger the baby, the lower the recommended dose.

Furazolidone is a drug from the group of nitrofurans with antibacterial properties.

The duration of the course of treatment is determined individually. On average, it ranges from five to ten days. Children are not recommended to take the drug for more than ten days. As an alternative, a treatment regimen can be used that provides for cyclic administration of the drug. The first cycle lasts three to six days, followed by a three-day break and a second cycle.

The treatment of burns and infected wounds with furazolidone deserves special attention. To do this, use a solution in which the ratio of the amount of medicine and water is 1:25000. To prepare it, take 2 tablets of the drug and 250 ml of warm boiled water. The tablets are crushed and mixed with water. The resulting product is washed with wounds, wet bandages are applied.

Side effects

Judging by the reviews, the drug is well tolerated, as it has a low level of toxicity. But, as with any other medication, undesirable effects may develop during treatment with furazolidone.

The main ones include:

  • nausea;
  • vomit;
  • loss of appetite;
  • pain in the epigastric region;
  • skin rash;
  • allergic dermatitis by the type of urticaria;
  • angioedema;
  • hemolysis of erythrocytes;
  • dyspnea;
  • cough;
  • increased body temperature;
  • neurotoxic reactions in the form of focal symptoms of brain damage.

The latter side effects are very rare. As a rule, they are caused by an excess of the duration of treatment recommended in the instructions for use, the administration of the drug to newborn children.

Furazolidone causes a series of side effects such as vomiting, decreased appetite, abdominal pain

If one or more of these symptoms occur, stop taking the medicine and tell your doctor as soon as possible.

There is no specific antidote for furazolidone. Patients are recommended general detoxification measures - gastric lavage, saline laxatives or enema, sorbents. With severe vomiting and dehydration, the treatment is supplemented with a correction of the water and electrolyte balance. With polyneuritis, it is definitely recommended to take vitamin B - it helps to restore damaged nerve fibers. If the dosage is exceeded in a patient suffering from renal insufficiency, as well as in case of severe poisoning, hemodialysis is performed - blood purification using an "artificial kidney".

Contraindications

Furazolidone should not be prescribed in such cases:

  • child's age - up to 1 year;
  • hypersensitivity to the active substance or auxiliary components;
  • chronic renal failure in the terminal stage;
  • lactose intolerance.

Furazolidone is prescribed with extreme caution to children suffering from liver pathology, especially if it is accompanied by functional organ failure. It is also necessary to carefully weigh the risks in diseases of the central and peripheral nervous system.

No matter how old the child is, he should not be given any drugs without consulting a doctor, even if the reviews about him are only positive. Only a specialist can choose the remedy that will be optimal in each case.

Ekaterina, 27-06-2016, 13:22 How much to give Furazolidone to a child for diarrhea?

Hello! The child is 4 and a half years old, weight 18 kg, height 118 cm. In the morning loose stools, almost every half an hour. How and how much can you drink Furazolidone?

Specialist's answer

Moshovis_Anna Family doctor

Good evening!

First of all, which is especially important for children, you need to know the exact cause of diarrhea. It can be caused by dietary habits, stress, and yes, bacterial agents. Which are also diverse and are treated, respectively, in different ways.

Furazolidone is used to treat dysentery, giardiasis, food poisoning, paratyphoid, typhoid fever and to destroy some other microorganisms that are sensitive to the action of the drug.

For children, the drug is prescribed at a dose of 10 mg per kg of body weight. That is, 180 mg is the daily dose for your child. We divide the dose into 3-4 doses. 1 tablet - 50 mg.

The drug is taken no more than 10 days. It is difficult to say how many days in your case, since the cause of diarrhea is not clear. Therefore, I strongly recommend that you contact the district pediatrician, who will prescribe the necessary examination and adjust the treatment. You may need to consult an infectious disease specialist.

Get well!

!

Consultation on the topic "How much to give Furazolidone to a child from diarrhea?" is given for reference purposes only. Based on the results of the consultation received, please consult a doctor, including to identify possible contraindications.